Standard Query      Browse by publication      Bulk download

Following publications are currently indexed in AREsite:

Jump to: 2010 (7) | 2009 (12) | 2008 (16) | 2007 (10) | 2006 (12) | 2005 (10) | 2004 (6) | 2003 (7) | 2002 (5) | 2001 (8) | 2000 (5) | 1999 (3) | 1998 (5) | 1996 (2)

2010

Hydrogen peroxide induces p16(INK4a) through an AUF1-dependent manner.
Guo GE, Ma LW, Jiang B, Yi J, Tong TJ, Wang WG
J Cell Biochem 2010; 109(5): 1000-5.   |  Show genes reported in this publication

AUF1 is involved in splenic follicular B cell maintenance.
Sadri N, Lu JY, Badura ML, Schneider RJ
BMC Immunol 2010; 11: 1.   |  Show genes reported in this publication

HuR/methyl-HuR and AUF1 regulate the MAT expressed during liver proliferation, differentiation, and carcinogenesis.
Vázquez-Chantada M, Fernández-Ramos D, Embade N, Martínez-Lopez N, Varela-Rey M, Woodhoo A, Luka Z, Wagner C, Anglim PP, Finnell RH, Caballería J, Laird-Offringa IA, Gorospe M, Lu SC, Mato JM, Martínez-Chantar ML
Gastroenterology 2010; 138(5): 1943-53.   |  Show genes reported in this publication

The RNA binding protein tristetraprolin influences the activation state of murine dendritic cells.
Bros M, Wiechmann N, Besche V, Art J, Pautz A, Grabbe S, Kleinert H, Reske-Kunz AB
Mol Immunol 2010; 47(5): 1161-70.   |  Show genes reported in this publication

Tristetraprolin regulates expression of VEGF and tumorigenesis in human colon cancer.
Lee HH, Son YJ, Lee WH, Park YW, Chae SW, Cho WJ, Kim YM, Choi HJ, Choi DH, Jung SW, Min YJ, Park SE, Lee BJ, Cha HJ, Park JW
Int J Cancer 2010; 126(8): 1817-27.   |  Show genes reported in this publication

The RNA-binding zinc-finger protein tristetraprolin regulates AU-rich mRNAs involved in breast cancer-related processes.
Al-Souhibani N, Al-Ahmadi W, Hesketh JE, Blackshear PJ, Khabar KS
Oncogene 2010; 29(29): 4205-15.   |  Show genes reported in this publication

Tristetraprolin regulates the stability of HIF-1alpha mRNA during prolonged hypoxia.
Kim TW, Yim S, Choi BJ, Jang Y, Lee JJ, Sohn BH, Yoo HS, Yeom YI, Park KC
Biochem Biophys Res Commun 2010; 391(1): 963-8.   |  Show genes reported in this publication

2009

Stability of eukaryotic translation initiation factor 4E mRNA is regulated by HuR, and this activity is dysregulated in cancer.
Topisirovic I, Siddiqui N, Orolicki S, Skrabanek LA, Tremblay M, Hoang T, Borden KL
Mol Cell Biol 2009; 29(5): 1152-62.   |  Show genes reported in this publication

Similar regulation of human inducible nitric-oxide synthase expression by different isoforms of the RNA-binding protein AUF1.
Pautz A, Linker K, Altenhöfer S, Heil S, Schmidt N, Art J, Knauer S, Stauber R, Sadri N, Pont A, Schneider RJ, Kleinert H
J Biol Chem 2009; 284(5): 2755-66.   |  Show genes reported in this publication

Identification of a signature motif in target mRNAs of RNA-binding protein AUF1.
Mazan-Mamczarz K, Kuwano Y, Zhan M, White EJ, Martindale JL, Lal A, Gorospe M
Nucleic Acids Res 2009; 37(1): 204-14.   |  Show genes reported in this publication

Auf1/Hnrnpd-deficient mice develop pruritic inflammatory skin disease.
Sadri N, Schneider RJ
J Invest Dermatol 2009; 129(3): 657-70.   |  Show genes reported in this publication

Coordinated posttranscriptional mRNA population dynamics during T-cell activation.
Mukherjee N, Lager PJ, Friedersdorf MB, Thompson MA, Keene JD
Mol Syst Biol 2009; 5: 288.   |  Show genes reported in this publication

The p38 MAPK pathway inhibits tristetraprolin-directed decay of interleukin-10 and pro-inflammatory mediator mRNAs in murine macrophages.
Tudor C, Marchese FP, Hitti E, Aubareda A, Rawlinson L, Gaestel M, Blackshear PJ, Clark AR, Saklatvala J, Dean JL
FEBS Lett 2009; 583(12): 1933-8.   |  Show genes reported in this publication

Tristetraprolin is required for full anti-inflammatory response of murine macrophages to IL-10.
Schaljo B, Kratochvill F, Gratz N, Sadzak I, Sauer I, Hammer M, Vogl C, Strobl B, Müller M, Blackshear PJ, Poli V, Lang R, Murray PJ, Kovarik P
J Immunol 2009; 183(2): 1197-206.   |  Show genes reported in this publication

Tristetraprolin mediates interferon-gamma mRNA decay.
Ogilvie RL, Sternjohn JR, Rattenbacher B, Vlasova IA, Williams DA, Hau HH, Blackshear PJ, Bohjanen PR
J Biol Chem 2009; 284(17): 11216-23.   |  Show genes reported in this publication

Stimulation of polo-like kinase 3 mRNA decay by tristetraprolin.
Horner TJ, Lai WS, Stumpo DJ, Blackshear PJ
Mol Cell Biol 2009; 29(8): 1999-2010.   |  Show genes reported in this publication

The mRNA decay factor tristetraprolin (TTP) induces senescence in human papillomavirus-transformed cervical cancer cells by targeting E6-AP ubiquitin ligase.
Sanduja S, Kaza V, Dixon DA
Aging (Albany NY) 2009; 1(9): 803-17.   |  Show genes reported in this publication

Tristetraprolin regulates IL-8 mRNA stability in cystic fibrosis lung epithelial cells.
Balakathiresan NS, Bhattacharyya S, Gutti U, Long RP, Jozwik C, Huang W, Srivastava M, Pollard HB, Biswas R
Am J Physiol Lung Cell Mol Physiol 2009; 296(6): L1012-8.   |  Show genes reported in this publication

The mRNA binding proteins HuR and tristetraprolin regulate cyclooxygenase 2 expression during colon carcinogenesis.
Young LE, Sanduja S, Bemis-Standoli K, Pena EA, Price RL, Dixon DA
Gastroenterology 2009; 136(5): 1669-79.   |  Show genes reported in this publication

2008

AUF1 and HuR proteins stabilize interleukin-8 mRNA in human saliva.
Palanisamy V, Park NJ, Wang J, Wong DT
J Dent Res 2008; 87(8): 772-6.   |  Show genes reported in this publication

Chaperone Hsp27, a novel subunit of AUF1 protein complexes, functions in AU-rich element-mediated mRNA decay.
Sinsimer KS, Gratacós FM, Knapinska AM, Lu J, Krause CD, Wierzbowski AV, Maher LR, Scrudato S, Rivera YM, Gupta S, Turrin DK, De La Cruz MP, Pestka S, Brewer G
Mol Cell Biol 2008; 28(17): 5223-37.   |  Show genes reported in this publication

ElrA and AUF1 differentially bind cyclin B2 mRNA.
Guo X, Gourronc F, Audic Y, Lyons-Levy G, Mitchell T, Hartley RS
Biochem Biophys Res Commun 2008; 377(2): 653-7.   |  Show genes reported in this publication

AUF1 isoform-specific regulation of anti-inflammatory IL10 expression in monocytes.
Sarkar S, Sinsimer KS, Foster RL, Brewer G, Pestka S
J Interferon Cytokine Res 2008; 28(11): 679-91.   |  Show genes reported in this publication

AUF1 is upregulated by angiotensin II to destabilize cardiac Kv4.3 channel mRNA.
Zhou C, Vignere CZ, Levitan ES
J Mol Cell Cardiol 2008; 45(6): 832-8.   |  Show genes reported in this publication

The mRNA decay promoting factor K-homology splicing regulator protein post-transcriptionally determines parathyroid hormone mRNA levels.
Nechama M, Ben-Dov IZ, Briata P, Gherzi R, Naveh-Many T
FASEB J 2008; 22(10): 3458-68.   |  Show genes reported in this publication

RNA-binding proteins HuR and PTB promote the translation of hypoxia-inducible factor 1alpha.
Galbán S, Kuwano Y, Pullmann R, Martindale JL, Kim HH, Lal A, Abdelmohsen K, Yang X, Dang Y, Liu JO, Lewis SM, Holcik M, Gorospe M
Mol Cell Biol 2008; 28(1): 93-107.   |  Show genes reported in this publication

MKP-1 mRNA stabilization and translational control by RNA-binding proteins HuR and NF90.
Kuwano Y, Kim HH, Abdelmohsen K, Pullmann R, Martindale JL, Yang X, Gorospe M
Mol Cell Biol 2008; 28(14): 4562-75.   |  Show genes reported in this publication

Genome-wide analysis identifies interleukin-10 mRNA as target of tristetraprolin.
Stoecklin G, Tenenbaum SA, Mayo T, Chittur SV, George AD, Baroni TE, Blackshear PJ, Anderson P
J Biol Chem 2008; 283(17): 11689-99.   |  Show genes reported in this publication

Targeting mRNA stability arrests inflammatory bone loss.
Patil CS, Liu M, Zhao W, Coatney DD, Li F, VanTubergen EA, D'Silva NJ, Kirkwood KL
Mol Ther 2008; 16(10): 1657-64.   |  Show genes reported in this publication

Tristetraprolin regulates TNF TNF-alpha mRNA stability via a proteasome dependent mechanism involving the combined action of the ERK and p38 pathways.
Deleault KM, Skinner SJ, Brooks SA
Mol Immunol 2008; 45(1): 13-24.   |  Show genes reported in this publication

Post-transcriptional regulation of CLMP mRNA is controlled by tristetraprolin in response to TNFalpha via c-Jun N-terminal kinase signalling.
Sze KL, Lui WY, Lee WM
Biochem J 2008; 410(3): 575-83.   |  Show genes reported in this publication

Modulation of immediate early gene expression by tristetraprolin in the differentiation of 3T3-L1 cells.
Lin NY, Lin CT, Chang CJ
Biochem Biophys Res Commun 2008; 365(1): 69-74.   |  Show genes reported in this publication

Tristetraprolin down-regulates interleukin-8 and vascular endothelial growth factor in malignant glioma cells.
Suswam E, Li Y, Zhang X, Gillespie GY, Li X, Shacka JJ, Lu L, Zheng L, King PH
Cancer Res 2008; 68(3): 674-82.   |  Show genes reported in this publication

Tristetraprolin regulates CXCL1 (KC) mRNA stability.
Datta S, Biswas R, Novotny M, Pavicic PG, Herjan T, Mandal P, Hamilton TA
J Immunol 2008; 180(4): 2545-52.   |  Show genes reported in this publication

Identification of TTP mRNA targets in human dendritic cells reveals TTP as a critical regulator of dendritic cell maturation.
Emmons J, Townley-Tilson WH, Deleault KM, Skinner SJ, Gross RH, Whitfield ML, Brooks SA
RNA 2008; 14(5): 888-902.   |  Show genes reported in this publication

2007

Analysis of turnover and translation regulatory RNA-binding protein expression through binding to cognate mRNAs.
Pullmann R, Kim HH, Abdelmohsen K, Lal A, Martindale JL, Yang X, Gorospe M
Mol Cell Biol 2007; 27(18): 6265-78.   |  Show genes reported in this publication

Involvement of RNA binding proteins AUF1 in mammary gland differentiation.
Nagaoka K, Tanaka T, Imakawa K, Sakai S
Exp Cell Res 2007; 313(13): 2937-45.   |  Show genes reported in this publication

Competitive binding of AUF1 and TIAR to MYC mRNA controls its translation.
Liao B, Hu Y, Brewer G
Nat Struct Mol Biol 2007; 14(6): 511-8.   |  Show genes reported in this publication

AUF1 cell cycle variations define genomic DNA methylation by regulation of DNMT1 mRNA stability.
Torrisani J, Unterberger A, Tendulkar SR, Shikimi K, Szyf M
Mol Cell Biol 2007; 27(1): 395-410.   |  Show genes reported in this publication

The RNA-binding protein HuR promotes cell migration and cell invasion by stabilizing the beta-actin mRNA in a U-rich-element-dependent manner.
Dormoy-Raclet V, Ménard I, Clair E, Kurban G, Mazroui R, Di Marco S, von Roretz C, Pause A, Gallouzi IE
Mol Cell Biol 2007; 27(15): 5365-80.   |  Show genes reported in this publication

Regulation of suppressor of cytokine signaling 3 (SOCS3) mRNA stability by TNF-alpha involves activation of the MKK6/p38MAPK/MK2 cascade.
Ehlting C, Lai WS, Schaper F, Brenndörfer ED, Matthes RJ, Heinrich PC, Ludwig S, Blackshear PJ, Gaestel M, Häussinger D, Bode JG
J Immunol 2007; 178(5): 2813-26.   |  Show genes reported in this publication

Tristetraprolin recruits functional mRNA decay complexes to ARE sequences.
Hau HH, Walsh RJ, Ogilvie RL, Williams DA, Reilly CS, Bohjanen PR
J Cell Biochem 2007; 100(6): 1477-92.   |  Show genes reported in this publication

Tristetraprolin inhibits Ras-dependent tumor vascularization by inducing vascular endothelial growth factor mRNA degradation.
Essafi-Benkhadir K, Onesto C, Stebe E, Moroni C, Pagès G
Mol Biol Cell 2007; 18(11): 4648-58.   |  Show genes reported in this publication

Tristetraprolin, a negative regulator of mRNA stability, is increased in old B cells and is involved in the degradation of E47 mRNA.
Frasca D, Landin AM, Alvarez JP, Blackshear PJ, Riley RL, Blomberg BB
J Immunol 2007; 179(2): 918-27.   |  Show genes reported in this publication

Regulation of tristetraprolin during differentiation of 3T3-L1 preadipocytes.
Lin NY, Lin CT, Chen YL, Chang CJ
FEBS J 2007; 274(3): 867-78.   |  Show genes reported in this publication

2006

Posttranscriptional derepression of GADD45alpha by genotoxic stress.
Lal A, Abdelmohsen K, Pullmann R, Kawai T, Galban S, Yang X, Brewer G, Gorospe M
Mol Cell 2006; 22(1): 117-28.   |  Show genes reported in this publication

Endotoxic shock in AUF1 knockout mice mediated by failure to degrade proinflammatory cytokine mRNAs.
Lu JY, Sadri N, Schneider RJ
Genes Dev 2006; 20(22): 3174-84.   |  Show genes reported in this publication

JNK activation decreases PP2A regulatory subunit B56alpha expression and mRNA stability and increases AUF1 expression in cardiomyocytes.
Glaser ND, Lukyanenko YO, Wang Y, Wilson GM, Rogers TB
Am J Physiol Heart Circ Physiol 2006; 291(3): H1183-92.   |  Show genes reported in this publication

Destabilization of interleukin-6 mRNA requires a putative RNA stem-loop structure, an AU-rich element, and the RNA-binding protein AUF1.
Paschoud S, Dogar AM, Kuntz C, Grisoni-Neupert B, Richman L, Kühn LC
Mol Cell Biol 2006; 26(22): 8228-41.   |  Show genes reported in this publication

Increased parathyroid hormone gene expression in secondary hyperparathyroidism of experimental uremia is reversed by calcimimetics: correlation with posttranslational modification of the trans acting factor AUF1.
Levi R, Ben-Dov IZ, Lavi-Moshayoff V, Dinur M, Martin D, Naveh-Many T, Silver J
J Am Soc Nephrol 2006; 17(1): 107-12.   |  Show genes reported in this publication

HuR contributes to cyclin E1 deregulation in MCF-7 breast cancer cells.
Guo X, Hartley RS
Cancer Res 2006; 66(16): 7948-56.   |  Show genes reported in this publication

Wnt-5a mRNA translation is suppressed by the Elav-like protein HuR in human breast epithelial cells.
Leandersson K, Riesbeck K, Andersson T
Nucleic Acids Res 2006; 34(14): 3988-99.   |  Show genes reported in this publication

Interferons limit inflammatory responses by induction of tristetraprolin.
Sauer I, Schaljo B, Vogl C, Gattermeier I, Kolbe T, Müller M, Blackshear PJ, Kovarik P
Blood 2006; 107(12): 4790-7.   |  Show genes reported in this publication

Novel mRNA targets for tristetraprolin (TTP) identified by global analysis of stabilized transcripts in TTP-deficient fibroblasts.
Lai WS, Parker JS, Grissom SF, Stumpo DJ, Blackshear PJ
Mol Cell Biol 2006; 26(24): 9196-208.   |  Show genes reported in this publication

Tristetraprolin regulates Cyclin D1 and c-Myc mRNA stability in response to rapamycin in an Akt-dependent manner via p38 MAPK signaling.
Marderosian M, Sharma A, Funk AP, Vartanian R, Masri J, Jo OD, Gera JF
Oncogene 2006; 25(47): 6277-90.   |  Show genes reported in this publication

Down-regulation of tristetraprolin expression results in enhanced IL-12 and MIP-2 production and reduced MIP-3alpha synthesis in activated macrophages.
Jalonen U, Nieminen R, Vuolteenaho K, Kankaanranta H, Moilanen E
Mediators Inflamm 2006; 2006(6): 40691.   |  Show genes reported in this publication

Differential regulation of ARE-mediated TNFalpha and IL-1beta mRNA stability by lipopolysaccharide in RAW264.7 cells.
Chen YL, Huang YL, Lin NY, Chen HC, Chiu WC, Chang CJ
Biochem Biophys Res Commun 2006; 346(1): 160-8.   |  Show genes reported in this publication

2005

A hairpin-like structure within an AU-rich mRNA-destabilizing element regulates trans-factor binding selectivity and mRNA decay kinetics.
Fialcowitz EJ, Brewer BY, Keenan BP, Wilson GM
J Biol Chem 2005; 280(23): 22406-17.   |  Show genes reported in this publication

The peptidyl-prolyl isomerase Pin1 regulates the stability of granulocyte-macrophage colony-stimulating factor mRNA in activated eosinophils.
Shen ZJ, Esnault S, Malter JS
Nat Immunol 2005; 6(12): 1280-7.   |  Show genes reported in this publication

The c-Yes 3'-UTR contains adenine/uridine-rich elements that bind AUF1 and HuR involved in mRNA decay in breast cancer cells.
Sommer S, Cui Y, Brewer G, Fuqua SA
J Steroid Biochem Mol Biol 2005; 97(3): 219-29.   |  Show genes reported in this publication

Identification and characterization of cis-acting elements in the human and bovine PTH mRNA 3'-untranslated region.
Bell O, Silver J, Naveh-Many T
J Bone Miner Res 2005; 20(5): 858-66.   |  Show genes reported in this publication

Increased stability of the p16 mRNA with replicative senescence.
Wang W, Martindale JL, Yang X, Chrest FJ, Gorospe M
EMBO Rep 2005; 6(2): 158-64.   |  Show genes reported in this publication

Interaction of RNA-binding proteins HuR and AUF1 with the human ATF3 mRNA 3'-untranslated region regulates its amino acid limitation-induced stabilization.
Pan YX, Chen H, Kilberg MS
J Biol Chem 2005; 280(41): 34609-16.   |  Show genes reported in this publication

Antiapoptotic function of RNA-binding protein HuR effected through prothymosin alpha.
Lal A, Kawai T, Yang X, Mazan-Mamczarz K, Gorospe M
EMBO J 2005; 24(10): 1852-62.   |  Show genes reported in this publication

Tristetraprolin regulates the expression of the human inducible nitric-oxide synthase gene.
Fechir M, Linker K, Pautz A, Hubrich T, Förstermann U, Rodriguez-Pascual F, Kleinert H
Mol Pharmacol 2005; 67(6): 2148-61.   |  Show genes reported in this publication

Involvement of KSRP in the post-transcriptional regulation of human iNOS expression-complex interplay of KSRP with TTP and HuR.
Linker K, Pautz A, Fechir M, Hubrich T, Greeve J, Kleinert H
Nucleic Acids Res 2005; 33(15): 4813-27.   |  Show genes reported in this publication

Tristetraprolin down-regulates IL-2 gene expression through AU-rich element-mediated mRNA decay.
Ogilvie RL, Abelson M, Hau HH, Vlasova I, Blackshear PJ, Bohjanen PR
J Immunol 2005; 174(2): 953-61.   |  Show genes reported in this publication

2004

Concurrent versus individual binding of HuR and AUF1 to common labile target mRNAs.
Lal A, Mazan-Mamczarz K, Kawai T, Yang X, Martindale JL, Gorospe M
EMBO J 2004; 23(15): 3092-102.   |  Show genes reported in this publication

Expression of the SH2D1A gene is regulated by a combination of transcriptional and post-transcriptional mechanisms.
Okamoto S, Ji H, Howie D, Clarke K, Gullo C, Manning S, Coyle AJ, Terhorst C
Eur J Immunol 2004; 34(11): 3176-86.   |  Show genes reported in this publication

Stability of A+U-rich element binding factor 1 (AUF1)-binding messenger ribonucleic acid correlates with the subcellular relocalization of AUF1 in the rat uterus upon estrogen treatment.
Arao Y, Kikuchi A, Kishida M, Yonekura M, Inoue A, Yasuda S, Wada S, Ikeda K, Kayama F
Mol Endocrinol 2004; 18(9): 2255-67.   |  Show genes reported in this publication

Interaction between 3' untranslated region of calcitonin receptor messenger ribonucleic acid (RNA) and adenylate/uridylate (AU)-rich element binding proteins (AU-rich RNA-binding factor 1 and Hu antigen R).
Yasuda S, Wada S, Arao Y, Kogawa M, Kayama F, Katayama S
Endocrinology 2004; 145(4): 1730-8.   |  Show genes reported in this publication

Identification of a target RNA motif for RNA-binding protein HuR.
López de Silanes I, Zhan M, Lal A, Yang X, Gorospe M
Proc Natl Acad Sci U S A 2004; 101(9): 2987-92.   |  Show genes reported in this publication

The role of mRNA turnover in the regulation of tristetraprolin expression: evidence for an extracellular signal-regulated kinase-specific, AU-rich element-dependent, autoregulatory pathway.
Brooks SA, Connolly JE, Rigby WF
J Immunol 2004; 172(12): 7263-71.   |  Show genes reported in this publication

2003

Increased interleukin-10 mRNA stability in melanoma cells is associated with decreased levels of A + U-rich element binding factor AUF1.
Brewer G, Saccani S, Sarkar S, Lewis A, Pestka S
J Interferon Cytokine Res 2003; 23(10): 553-64.   |  Show genes reported in this publication

The 3'-UTR of the mRNA coding for the major protein kinase C substrate MARCKS contains a novel CU-rich element interacting with the mRNA stabilizing factors HuD and HuR.
Wein G, Rössler M, Klug R, Herget T
Eur J Biochem 2003; 270(2): 350-65.   |  Show genes reported in this publication

RNA-binding protein HuR enhances p53 translation in response to ultraviolet light irradiation.
Mazan-Mamczarz K, Galbán S, López de Silanes I, Martindale JL, Atasoy U, Keene JD, Gorospe M
Proc Natl Acad Sci U S A 2003; 100(14): 8354-9.   |  Show genes reported in this publication

The RNA-binding protein HuR regulates the expression of cyclooxygenase-2.
Sengupta S, Jang BC, Wu MT, Paik JH, Furneaux H, Hla T
J Biol Chem 2003; 278(27): 25227-33.   |  Show genes reported in this publication

A novel mechanism of tumor suppression by destabilizing AU-rich growth factor mRNA.
Stoecklin G, Gross B, Ming XF, Moroni C
Oncogene 2003; 22(23): 3554-61.   |  Show genes reported in this publication

Tristetraprolin binds to the 3'-untranslated region of cyclooxygenase-2 mRNA. A polyadenylation variant in a cancer cell line lacks the binding site.
Sawaoka H, Dixon DA, Oates JA, Boutaud O
J Biol Chem 2003; 278(16): 13928-35.   |  Show genes reported in this publication

Tristetraprolin binds to the COX-2 mRNA 3' untranslated region in cancer cells.
Boutaud O, Dixon DA, Oates JA, Sawaoka H
Adv Exp Med Biol 2003; 525: 157-60.   |  Show genes reported in this publication

2002

AUF1 Is a bcl-2 A + U-rich element-binding protein involved in bcl-2 mRNA destabilization during apoptosis.
Lapucci A, Donnini M, Papucci L, Witort E, Tempestini A, Bevilacqua A, Nicolin A, Brewer G, Schiavone N, Capaccioli S
J Biol Chem 2002; 277(18): 16139-46.   |  Show genes reported in this publication

A new player in oncogenesis: AUF1/hnRNPD overexpression leads to tumorigenesis in transgenic mice.
Gouble A, Grazide S, Meggetto F, Mercier P, Delsol G, Morello D
Cancer Res 2002; 62(5): 1489-95.   |  Show genes reported in this publication

IL-1 beta transcript stability in monocytes is linked to cytoskeletal reorganization and the availability of mRNA degradation factors.
Sirenko O, Böcker U, Morris JS, Haskill JS, Watson JM
Immunol Cell Biol 2002; 80(4): 328-39.   |  Show genes reported in this publication

Correlation between intrinsic mRNA stability and the affinity of AUF1 (hnRNP D) and HuR for A+U-rich mRNAs.
Blaxall BC, Pende A, Wu SC, Port JD
Mol Cell Biochem 2002; 232(1-2): 1-11.   |  Show genes reported in this publication

Highly selective actions of HuR in antagonizing AU-rich element-mediated mRNA destabilization.
Chen CY, Xu N, Shyu AB
Mol Cell Biol 2002; 22(20): 7268-78.   |  Show genes reported in this publication

2001

Folding of A+U-rich RNA elements modulates AUF1 binding. Potential roles in regulation of mRNA turnover.
Wilson GM, Sutphen K, Chuang Ky , Brewer G
J Biol Chem 2001; 276(12): 8695-704.   |  Show genes reported in this publication

Structural remodeling of an A + U-rich RNA element by cation or AUF1 binding.
Wilson GM, Sutphen K, Moutafis M, Sinha S, Brewer G
J Biol Chem 2001; 276(42): 38400-9.   |  Show genes reported in this publication

The 3' untranslated region of tumor necrosis factor alpha mRNA is a target of the mRNA-stabilizing factor HuR.
Dean JL, Wait R, Mahtani KR, Sully G, Clark AR, Saklatvala J
Mol Cell Biol 2001; 21(3): 721-30.   |  Show genes reported in this publication

HuR, a RNA stability factor, is expressed in malignant brain tumors and binds to adenine- and uridine-rich elements within the 3' untranslated regions of cytokine and angiogenic factor mRNAs.
Nabors LB, Gillespie GY, Harkins L, King PH
Cancer Res 2001; 61(5): 2154-61.   |  Show genes reported in this publication

HuA and tristetraprolin are induced following T cell activation and display distinct but overlapping RNA binding specificities.
Raghavan A, Robison RL, McNabb J, Miller CR, Williams DA, Bohjanen PR
J Biol Chem 2001; 276(51): 47958-65.   |  Show genes reported in this publication

Cellular mutants define a common mRNA degradation pathway targeting cytokine AU-rich elements.
Stoecklin G, Stoeckle P, Lu M, Muehlemann O, Moroni C
RNA 2001; 7(11): 1578-88.   |  Show genes reported in this publication

Parallel and independent regulation of interleukin-3 mRNA turnover by phosphatidylinositol 3-kinase and p38 mitogen-activated protein kinase.
Ming XF, Stoecklin G, Lu M, Looser R, Moroni C
Mol Cell Biol 2001; 21(17): 5778-89.   |  Show genes reported in this publication

Interactions of CCCH zinc finger proteins with mRNA: tristetraprolin-mediated AU-rich element-dependent mRNA degradation can occur in the absence of a poly(A) tail.
Lai WS, Blackshear PJ
J Biol Chem 2001; 276(25): 23144-54.   |  Show genes reported in this publication

2000

Identification of AUF1 as a parathyroid hormone mRNA 3'-untranslated region-binding protein that determines parathyroid hormone mRNA stability.
Sela-Brown A, Silver J, Brewer G, Naveh-Many T
J Biol Chem 2000; 275(10): 7424-9.   |  Show genes reported in this publication

HuR regulates p21 mRNA stabilization by UV light.
Wang W, Furneaux H, Cheng H, Caldwell MC, Hutter D, Liu Y, Holbrook N, Gorospe M
Mol Cell Biol 2000; 20(3): 760-9.   |  Show genes reported in this publication

HuR regulates cyclin A and cyclin B1 mRNA stability during cell proliferation.
Wang W, Caldwell MC, Lin S, Furneaux H, Gorospe M
EMBO J 2000; 19(10): 2340-50.   |  Show genes reported in this publication

Somatic mRNA turnover mutants implicate tristetraprolin in the interleukin-3 mRNA degradation pathway.
Stoecklin G, Ming XF, Looser R, Moroni C
Mol Cell Biol 2000; 20(11): 3753-63.   |  Show genes reported in this publication

Evidence that tristetraprolin is a physiological regulator of granulocyte-macrophage colony-stimulating factor messenger RNA deadenylation and stability.
Carballo E, Lai WS, Blackshear PJ
Blood 2000; 95(6): 1891-9.   |  Show genes reported in this publication

1999

Developmental regulation of RNA transcript destabilization by A + U-rich elements is AUF1-dependent.
Buzby JS, Brewer G, Nugent DJ
J Biol Chem 1999; 274(48): 33973-8.   |  Show genes reported in this publication

Identification of AUF-1 ligands reveals vast diversity of early response gene mRNAs.
Bhattacharya S, Giordano T, Brewer G, Malter JS
Nucleic Acids Res 1999; 27(6): 1464-72.   |  Show genes reported in this publication

Evidence that tristetraprolin binds to AU-rich elements and promotes the deadenylation and destabilization of tumor necrosis factor alpha mRNA.
Lai WS, Carballo E, Strum JR, Kennington EA, Phillips RS, Blackshear PJ
Mol Cell Biol 1999; 19(6): 4311-23.   |  Show genes reported in this publication

1998

Developmental expression of AUF1 and HuR, two c-myc mRNA binding proteins.
Lafon I, Carballès F, Brewer G, Poiret M, Morello D
Oncogene 1998; 16(26): 3413-21.   |  Show genes reported in this publication

RNA stabilization by the AU-rich element binding protein, HuR, an ELAV protein.
Peng SS, Chen CY, Xu N, Shyu AB
EMBO J 1998; 17(12): 3461-70.   |  Show genes reported in this publication

Overexpression of HuR, a nuclear-cytoplasmic shuttling protein, increases the in vivo stability of ARE-containing mRNAs.
Fan XC, Steitz JA
EMBO J 1998; 17(12): 3448-60.   |  Show genes reported in this publication

Hypoxic stabilization of vascular endothelial growth factor mRNA by the RNA-binding protein HuR.
Levy NS, Chung S, Furneaux H, Levy AP
J Biol Chem 1998; 273(11): 6417-23.   |  Show genes reported in this publication

Feedback inhibition of macrophage tumor necrosis factor-alpha production by tristetraprolin.
Carballo E, Lai WS, Blackshear PJ
Science 1998; 281(5379): 1001-5.   |  Show genes reported in this publication

1996

AUF1 binding affinity to A+U-rich elements correlates with rapid mRNA degradation.
DeMaria CT, Brewer G
J Biol Chem 1996; 271(21): 12179-84.   |  Show genes reported in this publication

Increased granulocyte-macrophage colony-stimulating factor mRNA instability in cord versus adult mononuclear cells is translation-dependent and associated with increased levels of A + U-rich element binding factor.
Buzby JS, Lee SM, Van Winkle P, DeMaria CT, Brewer G, Cairo MS
Blood 1996; 88(8): 2889-97.   |  Show genes reported in this publication